Whole-cell inactivated Leptospirosis vaccine: Future prospects

Inactivated African Horse Sickness Virus Cell Culture Vaccine

Incompatibility of lyophilized inactivated polio vaccine with liquid pentavalent whole-cell-pertussis-containing vaccine

A hexavalent vaccine containing diphtheria toxoid, tetanus toxoid, whole cell pertussis, Haemophilius influenza type B, hepatitis B and inactivated polio vaccine (IPV) may: (i) increase the efficiency of vaccination campaigns, (ii) reduce the number of injections thereby reducing needlestick injuries, and (iii) ensure better protection against pertussis as compared to vaccines containing acellu...

Vaccine coverage: recent trends and future prospects.

OBJECTIVE To assess the feasibility of achieving the target of 95% coverage for the childhood immunisation schedule by 1995 and to determine the influence of sociodemographic factors and information systems on recent trends. DESIGN Analyses of trends in quarterly vaccination data for diphtheria, pertussis, and measles in health districts between February 1988 and February 1991. SETTING Dist...

Characterization of a whole, inactivated influenza (H5N1) vaccine

OBJECTIVES Effective vaccines against the highly pathogenic influenza A/H5N1 virus are being developed worldwide. In Japan, two adjuvanted, inactivated, whole-virion influenza vaccines were recently developed and licensed as mock-up, pre-pandemic vaccine formulations by the Ministry of Health and Labor Welfare of Japan. During the vaccine design and development process, various obstacles were o...

Immunization against leptospirosis: vaccine trials with heat-killed whole cell and outer envelope antigens in hamsters.

Heat-killed whole cell and outer envelope antigens prepared from homologous virulent and avirulent strains of Leptospira serotypes canicola and pomona were evaluated for protecting hamsters against experimental leptospirosis. The heat-killed bacterins proved at least as effective as the outer envelope antigens, or more so, in providing protection against death and infection, and they are easier...